SO SÁNH HIỆU QUẢ KHỞI MÊ, THOÁT MÊ VÀ TÁC DỤNG TRÊN TUẦN HOÀN GIỮA GÂY MÊ KẾT HỢP PROPOFOL TCI VỚI KETAMIN VÀ ETOMIDAT VỚI SEVOFLURAN Ở NGƯỜI CAO TUỔI
نویسندگان
چکیده
Mục tiêu nghiên cứu này nhằm so sánh thời gian khởi mê, hồi tỉnh và ảnh hưởng trên nhịp tim, huyết áp giữa gây mê bằng propofol TCI kết hợp với Ketamin Etomidat sevofluran ở người cao tuổi. 210 bệnh nhân ≥ 60 tuổi, ASA I-II được ngẫu nhiên chia làm ba nhóm: nhóm 1 (n = 70) (Target Controlled Infusion) đặt nồng độ đích tại tương (Cp- plasma concentration); 2 não (Ce - effect site concentration). Cả ketamin 0,3 mg/kg, duy trì -TCI; 3 etomidat truyền tĩnh mạch tốc 0,05 mg/kg/phút, sevofluran. Ba cùng fentanyl 3µg/kg; rocuronium 0,8mg/kg để ống nội khí quản (NKQ). Kết quả: Thời chờ mất tri giác, đủ điều kiện NKQ, của ngắn hơn (p < 0,01). Tại điểm trước khi NKQ: tâm thu, trung bình thấp p 0,05; Sau tần số động 1, 0,001). rút NKQ 3.
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ژورنال
عنوان ژورنال: T?p chí Y h?c Vi?t Nam
سال: 2022
ISSN: ['1859-1868']
DOI: https://doi.org/10.51298/vmj.v519i1.3551